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Home Health & Lifestyle

Break-Through Cases of Measles: Vaccination Highest Priority Amidst Growing Outbreaks

Tasfia Jannat by Tasfia Jannat
April 6, 2025
in Health & Lifestyle
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Break-Through Cases of Measles: Vaccination Highest Priority Amidst Growing Outbreaks

Break-Through Cases of Measles: Vaccination Highest Priority Amidst Growing Outbreaks

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Where measles breakouts occur throughout a country, not only are cases being monitored among those who are unvaccinated but also in so-called breakthrough cases—instances when even completely vaccinated individuals contract the disease. They occur rarely, but they raise big questions regarding the efficacy of vaccines, immunity, as well as methods of controlling a country’s population.

Experts comment further that the strongest protection from severe illness, hospitalization, and also complications is vaccination. Indeed, elucidating the reasons breakthrough infections occur—and should not stop vaccination—is the most vital step in dispelling fears from the people.

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Why do measles breakthrough cases happen?

There’s no such things as a 100% foolproof vaccine, and measles is no different. Break-through infections can occur for a number of reasons:

1. Fading Immunity With Time


The measles vaccine, received twice in early life, gives most lifelong protection. Adult immunity, though, can decline in later life, especially in those vaccinated many years before. The vast majority are immune, but some become susceptible later in life.

2. Genetic Components and Immunity

Different people are also affected in a variety of ways by vaccines. There are some individuals, based on their genetic makeup, who respond more sluggishly or weakly, and are, therefore, more susceptible to infection in spite of being vaccinated.

3. Storing and Handling Vaccines

The measles-mumps-rubella (MMR) vaccination needs a set temperature in order to be effective. If the “cold chain” is disrupted, or if improper temperatures are used, the potency of the vaccine can be compromised.

Dr. Gregory Poland, director, co-director, and a vaccinologist of The Atria Research Institute, clarifies
“If the vaccine was not properly stored—left at room temperature or in the heat—then some recipients could have received a weakened strength dose they were not supposed to.”

4. High Exposure to Viruses

Measles is highly contagious—a good deal more so than influenza or even COVID-19. Vaccinated individuals sometimes become infected if they are exposed to quite large doses of the virus, usually in close or higher-risk environments.


Break-through infections are less dangerous.

The most important truth is this: vaccinated individuals who get measles suffer from less severe symptoms and outcomes than unvaccinated individuals. The evidence is supported by many studies:

  • A study in 2020 of a measles outbreak in the Netherlands during the period from 2013-2014 revealed no vaccinated patients were admitted or suffered complications, whereas 14.5% of the unvaccinated cases were admitted.
    A study, published in America in 2024, analyzing cases between the years of 2001-2022, identified that breakthrough infections caused:
  • 60% reduced complications
  • 70% lower hospitalization – **Reduces disease intensity by 50%

Dr. Poland, in explaining results, said

In those individuals who do get infected after they have been vaccinated, the illness is milder. The risk of serious complications—hospitalization, pneumonia, or encephalitis—is decreased dramatically.

Why Immunization is Still Important

Although random cases in succession are inescapable, the measles vaccine is one of the most effective health tools ever. Here’s why:

1. Measles is highly contagious.

  • A single infected person can infect 9 in every 10 unvaccinated close contacts with measles.

The virus survives for a maximum period of two hours in the air but wherever it has dropped, after the infected person has exited.

  1. Protecting Vulnerable Groups through Herd Immunity

For measles, we must achieve a minimum of a 95% rate of vaccination in a community in order not to suffer through the incidence. Without this, the virus has reservoirs of susceptibility, and where the breakouts occur—ones we are seeing in Florida, in Philadelphia, and in others.

Dr. Dan Barouch, a researcher at Harvard’s school of medicine, warns:

*Measles would rapidly spread in unimmunised populations. Outbreaks would continue as long as vaccination rates return.

  1. Immunization avoids severe complications

Even if the vaccinated individual does contract measles, they are:

  • Less likely to spread it to others.
  • Much less likely to get severely ill, such as with pneumonia, infection in the brain (encefalitis), or death.

What does Rael Dickey do?

1. Verify your vaccination status Adults born before 1989 may not have received more than a single dose of MMR. Two doses are today recommended by the CDC for maximum protection. – If unsure, a blood test can also test a person for measles immunity.

2. Vaccinate Yourself Before You Travel Measles occurs in most parts of the world. If overseas travel is planned, ensure your self, your children, and your family are up to date.

3. Don’t Panic About Break-through Cases No matter how good a vaccine is, however efficient, no vaccine can ever be a hundred percent effective. MMR does, though, lower the incidence of serious infection, and also the incidence of transmission, by a substantial degree. Low break-through rates do not decrease its worth. –

The Bottom Line

The recent outbreak is a salutary reminder of the danger of declining vaccination rates. Break-through infections, while theoretically a risk, are not frequent, usually mild—yet further good reason for the use of the vaccine. Good protection through vaccination depends upon herd immunity. Staying up to date, getting your immunity tested, and your family vaccinated are the best ways of preventing further breakdowns. Measles can be avoided. Vaccination is our best safeguard.

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